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Note:: Functional activity
All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
Morphology [Histology]
Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
Primary malignant neoplasms overlapping site boundaries
A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
Malignant neoplasm of ectopic tissue
Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).

C30

Malignant neoplasm of nasal cavity and middle ear [+]

C31

Malignant neoplasm of accessory sinuses [+]

C32

Malignant neoplasm of larynx [+]

Use additional	code to identify:
Use additional	alcohol abuse and dependence (F10.-)
Use additional	exposure to environmental tobacco smoke (Z77.22)
Use additional	exposure to tobacco smoke in the perinatal period (P96.81)
Use additional	history of tobacco dependence (Z87.891)
Use additional	occupational exposure to environmental tobacco smoke (Z57.31)
Use additional	tobacco dependence (F17.-)
Use additional	tobacco use (Z72.0)

C33

Malignant neoplasm of trachea

Use additional	code to identify:
Use additional	exposure to environmental tobacco smoke (Z77.22)
Use additional	exposure to tobacco smoke in the perinatal period (P96.81)
Use additional	history of tobacco dependence (Z87.891)
Use additional	occupational exposure to environmental tobacco smoke (Z57.31)
Use additional	tobacco dependence (F17.-)
Use additional	tobacco use (Z72.0)

C34

Malignant neoplasm of bronchus and lung [+]

Use additional	code to identify:
Use additional	exposure to environmental tobacco smoke (Z77.22)
Use additional	exposure to tobacco smoke in the perinatal period (P96.81)
Use additional	history of tobacco dependence (Z87.891)
Use additional	occupational exposure to environmental tobacco smoke (Z57.31)
Use additional	tobacco dependence (F17.-)
Use additional	tobacco use (Z72.0)
Excludes 1:	Kaposi's sarcoma of lung (C46.5-) malignant carcinoid tumor of the bronchus and lung (C7A.090)

C34.0

Malignant neoplasm of main bronchus [+]
Malignant neoplasm of carina
Malignant neoplasm of hilus (of lung)

C34.1

Malignant neoplasm of upper lobe, bronchus or lung [+]

Malignant neoplasm of middle lobe, bronchus or lung

C34.3

Malignant neoplasm of lower lobe, bronchus or lung [+]

C34.8

Malignant neoplasm of overlapping sites of bronchus and lung [+]

C34.9

Malignant neoplasm of unspecified part of bronchus or lung [+]

C37

Malignant neoplasm of thymus

Excludes 1:

malignant carcinoid tumor of the thymus (C7A.091)

C38

Malignant neoplasm of heart, mediastinum and pleura [+]

Excludes 1:

mesothelioma (C45.-)

C39

Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs [+]

Use additional	code to identify:
Use additional	exposure to environmental tobacco smoke (Z77.22)
Use additional	exposure to tobacco smoke in the perinatal period (P96.81)
Use additional	history of tobacco dependence (Z87.891)
Use additional	occupational exposure to environmental tobacco smoke (Z57.31)
Use additional	tobacco dependence (F17.-)
Use additional	tobacco use (Z72.0)
Excludes 1:	intrathoracic malignant neoplasm NOS (C76.1) thoracic malignant neoplasm NOS (C76.1)