Neoplasms (C00-D49)

Note:
Functional activity
All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
Morphology [Histology]
Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
Primary malignant neoplasms overlapping site boundaries
A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
Malignant neoplasm of ectopic tissue
Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).

Malignant neoplasms of female genital organs (C51-C58)

Includes:
malignant neoplasm of skin of female genital organs
C51 Malignant neoplasm of vulva [+]
Excludes 1: carcinoma in situ of vulva (D07.1)
C52 Malignant neoplasm of vagina
Excludes 1: carcinoma in situ of vagina (D07.2)
C53 Malignant neoplasm of cervix uteri [+]
Excludes 1: carcinoma in situ of cervix uteri (D06.-)
C54 Malignant neoplasm of corpus uteri [+]
C55 Malignant neoplasm of uterus, part unspecified
C56 Malignant neoplasm of ovary [+]
Use additional code to identify any functional activity
C57 Malignant neoplasm of other and unspecified female genital organs [+]
C58 Malignant neoplasm of placenta
Includes: choriocarcinoma NOS
chorionepithelioma NOS
Excludes 1: chorioadenoma (destruens) (D39.2)
hydatidiform mole NOS (O01.9)
invasive hydatidiform mole (D39.2)
male choriocarcinoma NOS (C62.9-)
malignant hydatidiform mole (D39.2)

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