Neoplasms (C00-D49)

Note:
Functional activity
All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
Morphology [Histology]
Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
Primary malignant neoplasms overlapping site boundaries
A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
Malignant neoplasm of ectopic tissue
Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).

Malignant neoplasms of ill-defined, other secondary and unspecified sites (C76-C80)

C76 Malignant neoplasm of other and ill-defined sites [+]
Excludes 1: malignant neoplasm of female genitourinary tract NOS (C57.9)
malignant neoplasm of male genitourinary tract NOS (C63.9)
malignant neoplasm of lymphoid, hematopoietic and related tissue (C81-C96)
malignant neoplasm of skin (C44.-)
malignant neoplasm of unspecified site NOS (C80.1)
C77 Secondary and unspecified malignant neoplasm of lymph nodes [+]
Excludes 1: malignant neoplasm of lymph nodes, specified as primary (C81-C86, C88, C96.-)
mesentary metastasis of carcinoid tumor (C7B.04)
secondary carcinoid tumors of distant lymph nodes (C7B.01)
C78 Secondary malignant neoplasm of respiratory and digestive organs [+]
Excludes 1: secondary carcinoid tumors of liver (C7B.02)
secondary carcinoid tumors of peritoneum (C7B.04)
Excludes 2: lymph node metastases (C77.0)
C79 Secondary malignant neoplasm of other and unspecified sites [+]
Excludes 1: secondary carcinoid tumors (C7B.-)
secondary neuroendocrine tumors (C7B.-)
C80 Malignant neoplasm without specification of site [+]
Excludes 1: malignant carcinoid tumor of unspecified site (C7A.00)
malignant neoplasm of specified multiple sites- code to each site

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