Neoplasms (C00-D49)

Note:
Functional activity
All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
Morphology [Histology]
Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
Primary malignant neoplasms overlapping site boundaries
A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
Malignant neoplasm of ectopic tissue
Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).

Benign neoplasms, except benign neuroendocrine tumors (D10-D36)

D10 Benign neoplasm of mouth and pharynx [+]
D11 Benign neoplasm of major salivary glands [+]
Excludes 1: benign neoplasms of specified minor salivary glands which are classified according to their anatomical location
benign neoplasms of minor salivary glands NOS (D10.39)
D12 Benign neoplasm of colon, rectum, anus and anal canal [+]
Excludes 2: benign carcinoid tumors of the large intestine and rectum (D3A.02-)
polyp of colon NOS (K63.5)
D13 Benign neoplasm of other and ill-defined parts of digestive system [+]
Excludes 1: benign stromal tumors of digestive system (D21.4)
D14 Benign neoplasm of middle ear and respiratory system [+]
D15 Benign neoplasm of other and unspecified intrathoracic organs [+]
Excludes 1: benign neoplasm of mesothelial tissue (D19.-)
D16 Benign neoplasm of bone and articular cartilage [+]
Excludes 1: benign neoplasm of connective tissue of ear (D21.0)
benign neoplasm of connective tissue of eyelid (D21.0)
benign neoplasm of connective tissue of larynx (D14.1)
benign neoplasm of connective tissue of nose (D14.0)
benign neoplasm of synovia (D21.-)
D17 Benign lipomatous neoplasm [+]
D18 Hemangioma and lymphangioma, any site [+]
Excludes 1: benign neoplasm of glomus jugulare (D35.6)
blue or pigmented nevus (D22.-)
nevus NOS (D22.-)
vascular nevus (Q82.5)
D19 Benign neoplasm of mesothelial tissue [+]
D20 Benign neoplasm of soft tissue of retroperitoneum and peritoneum [+]
Excludes 1: benign lipomatous neoplasm of peritoneum and retroperitoneum (D17.79)
benign neoplasm of mesothelial tissue (D19.-)
D21 Other benign neoplasms of connective and other soft tissue [+]
Includes: benign neoplasm of blood vessel
benign neoplasm of bursa
benign neoplasm of cartilage
benign neoplasm of fascia
benign neoplasm of fat
benign neoplasm of ligament, except uterine
benign neoplasm of lymphatic channel
benign neoplasm of muscle
benign neoplasm of synovia
benign neoplasm of tendon (sheath)
benign stromal tumors
Excludes 1: benign neoplasm of articular cartilage (D16.-)
benign neoplasm of cartilage of larynx (D14.1)
benign neoplasm of cartilage of nose (D14.0)
benign neoplasm of connective tissue of breast (D24.-)
benign neoplasm of peripheral nerves and autonomic nervous system (D36.1-)
benign neoplasm of peritoneum (D20.1)
benign neoplasm of retroperitoneum (D20.0)
benign neoplasm of uterine ligament, any (D28.2)
benign neoplasm of vascular tissue (D18.-)
hemangioma (D18.0-)
lipomatous neoplasm (D17.-)
lymphangioma (D18.1)
uterine leiomyoma (D25.-)
D22 Melanocytic nevi [+]
Includes: atypical nevus
blue hairy pigmented nevus
nevus NOS
D23 Other benign neoplasms of skin [+]
Includes: benign neoplasm of hair follicles
benign neoplasm of sebaceous glands
benign neoplasm of sweat glands
Excludes 1: benign lipomatous neoplasms of skin (D17.0-D17.3)
Excludes 2: melanocytic nevi (D22.-)
D24 Benign neoplasm of breast [+]
Includes: benign neoplasm of connective tissue of breast
benign neoplasm of soft parts of breast
fibroadenoma of breast
Excludes 2: adenofibrosis of breast (N60.2)
benign cyst of breast (N60.-)
benign mammary dysplasia (N60.-)
benign neoplasm of skin of breast (D22.5, D23.5)
fibrocystic disease of breast (N60.-)
D25 Leiomyoma of uterus [+]
Includes: uterine fibroid
uterine fibromyoma
uterine myoma
D26 Other benign neoplasms of uterus [+]
D27 Benign neoplasm of ovary [+]
Use additional code to identify any functional activity.
Excludes 2: corpus albicans cyst (N83.2-)
corpus luteum cyst (N83.1-)
endometrial cyst (N80.1-)
follicular (atretic) cyst (N83.0-)
graafian follicle cyst (N83.0-)
ovarian cyst NEC (N83.2-)
ovarian retention cyst (N83.2-)
D28 Benign neoplasm of other and unspecified female genital organs [+]
Includes: adenomatous polyp
benign neoplasm of skin of female genital organs
benign teratoma
Excludes 1: epoophoron cyst (Q50.5)
fimbrial cyst (Q50.4)
Gartner's duct cyst (Q52.4)
parovarian cyst (Q50.5)
D29 Benign neoplasm of male genital organs [+]
Includes: benign neoplasm of skin of male genital organs
D30 Benign neoplasm of urinary organs [+]
D31 Benign neoplasm of eye and adnexa [+]
Excludes 1: benign neoplasm of connective tissue of eyelid (D21.0)
benign neoplasm of optic nerve (D33.3)
benign neoplasm of skin of eyelid (D22.1-, D23.1-)
D32 Benign neoplasm of meninges [+]
D33 Benign neoplasm of brain and other parts of central nervous system [+]
Excludes 1: angioma (D18.0-)
benign neoplasm of meninges (D32.-)
benign neoplasm of peripheral nerves and autonomic nervous system (D36.1-)
hemangioma (D18.0-)
neurofibromatosis (Q85.0-)
retro-ocular benign neoplasm (D31.6-)
D34 Benign neoplasm of thyroid gland
Use additional code to identify any functional activity
D35 Benign neoplasm of other and unspecified endocrine glands [+]
Use additional code to identify any functional activity
Excludes 1: benign neoplasm of endocrine pancreas (D13.7)
benign neoplasm of ovary (D27.-)
benign neoplasm of testis (D29.2.-)
benign neoplasm of thymus (D15.0)
D36 Benign neoplasm of other and unspecified sites [+]

Back to Previous Page