D55 |
Anemia due to enzyme disorders [+]
Excludes 1: |
drug-induced enzyme deficiency anemia (D59.2)
|
|
|
D55.0 |
Anemia due to glucose-6-phosphate dehydrogenase [G6PD] deficiency Favism G6PD deficiency anemia
Excludes 1: |
glucose-6-phosphate dehydrogenase (G6PD) deficiency without anemia (D75.A)
|
|
D55.1 |
Anemia due to other disorders of glutathione metabolism Anemia (due to) enzyme deficiencies, except G6PD, related to the hexose monophosphate [HMP] shunt pathway Anemia (due to) hemolytic nonspherocytic (hereditary), type I
|
D55.2 |
Anemia due to disorders of glycolytic enzymes [+]
Excludes 1: |
disorders of glycolysis not associated with anemia (E74.81-)
|
|
|
D55.21 |
Anemia due to pyruvate kinase deficiency PK deficiency anemia Pyruvate kinase deficiency anemia
|
D55.29 |
Anemia due to other disorders of glycolytic enzymes Hexokinase deficiency anemia Triose-phosphate isomerase deficiency anemia
|
|
D55.3 |
Anemia due to disorders of nucleotide metabolism
|
D55.8 |
Other anemias due to enzyme disorders
|
D55.9 |
Anemia due to enzyme disorder, unspecified
|
|
D56 |
Thalassemia [+]
Excludes 1: |
sickle-cell thalassemia (D57.4-)
|
|
|
D56.0 |
Alpha thalassemia Alpha thalassemia major Hemoglobin H Constant Spring Hemoglobin H disease Hydrops fetalis due to alpha thalassemia Severe alpha thalassemia Triple gene defect alpha thalassemia
Use additional |
code, if applicable, for hydrops fetalis due to alpha thalassemia (P56.99) |
Excludes 1: |
alpha thalassemia trait or minor (D56.3) asymptomatic alpha thalassemia (D56.3) hydrops fetalis due to isoimmunization (P56.0) hydrops fetalis not due to immune hemolysis (P83.2)
|
|
D56.1 |
Beta thalassemia Beta thalassemia major Cooley's anemia Homozygous beta thalassemia Severe beta thalassemia Thalassemia intermedia Thalassemia major
Excludes 1: |
beta thalassemia minor (D56.3) beta thalassemia trait (D56.3) delta-beta thalassemia (D56.2) hemoglobin E-beta thalassemia (D56.5) sickle-cell beta thalassemia (D57.4-)
|
|
D56.2 |
Delta-beta thalassemia Homozygous delta-beta thalassemia
Excludes 1: |
delta-beta thalassemia minor (D56.3) delta-beta thalassemia trait (D56.3)
|
|
D56.3 |
Thalassemia minor Alpha thalassemia minor Alpha thalassemia silent carrier Alpha thalassemia trait Beta thalassemia minor Beta thalassemia trait Delta-beta thalassemia minor Delta-beta thalassemia trait Thalassemia trait NOS
Excludes 1: |
alpha thalassemia (D56.0) beta thalassemia (D56.1) delta-beta thalassemia (D56.2) hemoglobin E-beta thalassemia (D56.5) sickle-cell trait (D57.3)
|
|
D56.4 |
Hereditary persistence of fetal hemoglobin [HPFH]
|
D56.5 |
Hemoglobin E-beta thalassemia
Excludes 1: |
beta thalassemia (D56.1) beta thalassemia minor (D56.3) beta thalassemia trait (D56.3) delta-beta thalassemia (D56.2) delta-beta thalassemia trait (D56.3) hemoglobin E disease (D58.2) other hemoglobinopathies (D58.2) sickle-cell beta thalassemia (D57.4-)
|
|
D56.8 |
Other thalassemias Dominant thalassemia Hemoglobin C thalassemia Mixed thalassemia Thalassemia with other hemoglobinopathy
Excludes 1: |
hemoglobin C disease (D58.2) hemoglobin E disease (D58.2) other hemoglobinopathies (D58.2) sickle-cell anemia (D57.-) sickle-cell thalassemia (D57.4-)
|
|
D56.9 |
Thalassemia, unspecified Mediterranean anemia (with other hemoglobinopathy)
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D57 |
Sickle-cell disorders [+]
Use additional |
code for any associated fever (R50.81) |
Excludes 1: |
other hemoglobinopathies (D58.-)
|
|
|
D57.0 |
Hb-SS disease with crisis [+] Sickle-cell disease with crisis Hb-SS disease with (vaso-occlusive) pain
|
|
D57.00 |
Hb-SS disease with crisis, unspecified Hb-SS disease with (painful) crisis NOS Hb-SS disease with (vaso-occlusive) pain NOS
|
D57.01 |
Hb-SS disease with acute chest syndrome
|
D57.02 |
Hb-SS disease with splenic sequestration
|
D57.03 |
Hb-SS disease with cerebral vascular involvement
Code also |
, if applicable, cerebral infarction (I63.-)
|
|
D57.04 |
Hb-SS disease with dactylitis
|
D57.09 |
Hb-SS disease with crisis with other specified complication
Use additional |
code to identify complications, such as: |
Use additional |
cholelithiasis (K80.-) |
Use additional |
priapism (N48.32) |
|
|
D57.1 |
Sickle-cell disease without crisis Hb-SS disease without crisis Sickle-cell anemia NOS Sickle-cell disease NOS Sickle-cell disorder NOS
|
D57.2 |
Sickle-cell/Hb-C disease [+] Hb-SC disease Hb-S/Hb-C disease
|
|
D57.20 |
Sickle-cell/Hb-C disease without crisis
|
D57.21 |
Sickle-cell/Hb-C disease with crisis [+]
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|
D57.211 |
Sickle-cell/Hb-C disease with acute chest syndrome
|
D57.212 |
Sickle-cell/Hb-C disease with splenic sequestration
|
D57.213 |
Sickle-cell/Hb-C disease with cerebral vascular involvement
Code also |
, if applicable, cerebral infarction (I63.-)
|
|
D57.214 |
Sickle-cell/Hb-C disease with dactylitis
|
D57.218 |
Sickle-cell/Hb-C disease with crisis with other specified complication
Use additional |
code to identify complications, such as: |
Use additional |
cholelithiasis (K80.-) |
Use additional |
priapism (N48.32) |
|
D57.219 |
Sickle-cell/Hb-C disease with crisis, unspecified Sickle-cell/Hb-C disease with crisis NOS Sickle-cell/Hb-C disease with (vaso-occlusive) pain NOS
|
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D57.3 |
Sickle-cell trait Hb-S trait Heterozygous hemoglobin S
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D57.4 |
Sickle-cell thalassemia [+] Sickle-cell beta thalassemia Thalassemia Hb-S disease
|
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D57.40 |
Sickle-cell thalassemia without crisis Microdrepanocytosis Sickle-cell thalassemia NOS
|
D57.41 |
Sickle-cell thalassemia, unspecified, with crisis [+] Sickle-cell thalassemia with (painful) crisis NOS Sickle-cell thalassemia with (vaso-occlusive) pain NOS
|
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D57.411 |
Sickle-cell thalassemia, unspecified, with acute chest syndrome
|
D57.412 |
Sickle-cell thalassemia, unspecified, with splenic sequestration
|
D57.413 |
Sickle-cell thalassemia, unspecified, with cerebral vascular involvement
Code also |
, if applicable cerebral infarction (I63.-)
|
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D57.414 |
Sickle-cell thalassemia, unspecified, with dactylitis
|
D57.418 |
Sickle-cell thalassemia, unspecified, with crisis with other specified complication
Use additional |
code to identify complications, such as: |
Use additional |
cholelithiasis (K80.-) |
Use additional |
priapism (N48.32) |
|
D57.419 |
Sickle-cell thalassemia, unspecified, with crisis Sickle-cell thalassemia with (painful) crisis NOS Sickle-cell thalassemia with (vaso-occlusive) pain NOS
|
|
D57.42 |
Sickle-cell thalassemia beta zero without crisis HbS-beta zero without crisis Sickle-cell beta zero without crisis
|
D57.43 |
Sickle-cell thalassemia beta zero with crisis [+] HbS-beta zero with crisis Sickle-cell beta zero with crisis
|
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D57.431 |
Sickle-cell thalassemia beta zero with acute chest syndrome HbS-beta zero with acute chest syndrome Sickle-cell beta zero with acute chest syndrome
|
D57.432 |
Sickle-cell thalassemia beta zero with splenic sequestration HbS-beta zero with splenic sequestration Sickle-cell beta zero with splenic sequestration
|
D57.433 |
Sickle-cell thalassemia beta zero with cerebral vascular involvement HbS-beta zero with cerebral vascular involvement Sickle-cell beta zero with cerebral vascular involvement
Code also |
, if applicable cerebral infarction (I63.-)
|
|
D57.434 |
Sickle-cell thalassemia beta zero with dactylitis
|
D57.438 |
Sickle-cell thalassemia beta zero with crisis with other specified complication HbS-beta zero with other specified complication Sickle-cell beta zero with other specified complication
Use additional |
code to identify complications, such as: |
Use additional |
cholelithiasis (K80.-) |
Use additional |
priapism (N48.32) |
|
D57.439 |
Sickle-cell thalassemia beta zero with crisis, unspecified HbS-beta zero with other specified complication Sickle-cell beta zero with crisis unspecified Sickle-cell thalassemia beta zero with (painful) crisis NOS Sickle-cell thalassemia beta zero with (vaso-occlusive) pain NOS
|
|
D57.44 |
Sickle-cell thalassemia beta plus without crisis HbS-beta plus without crisis Sickle-cell beta plus without crisis
|
D57.45 |
Sickle-cell thalassemia beta plus with crisis [+] HbS-beta plus with crisis Sickle-cell beta plus with crisis
|
|
D57.451 |
Sickle-cell thalassemia beta plus with acute chest syndrome HbS-beta plus with acute chest syndrome Sickle-cell beta plus with acute chest syndrome
|
D57.452 |
Sickle-cell thalassemia beta plus with splenic sequestration HbS-beta plus with splenic sequestration Sickle-cell beta plus with splenic sequestration
|
D57.453 |
Sickle-cell thalassemia beta plus with cerebral vascular involvement HbS-beta plus with cerebral vascular involvement Sickle-cell beta plus with cerebral vascular involvement
Code also |
, if applicable cerebral infarction (I63.-)
|
|
D57.454 |
Sickle-cell thalassemia beta plus with dactylitis
|
D57.458 |
Sickle-cell thalassemia beta plus with crisis with other specified complication HbS-beta plus with crisis with other specified complication Sickle-cell beta plus with crisis with other specified complication
Use additional |
code to identify complications, such as: |
Use additional |
cholelithiasis (K80.-) |
Use additional |
priapism (N48.32) |
|
D57.459 |
Sickle-cell thalassemia beta plus with crisis, unspecified HbS-beta plus with crisis with unspecified complication Sickle-cell beta plus with crisis with unspecified complication Sickle-cell thalassemia beta plus with (painful) crisis NOS Sickle-cell thalassemia beta plus with (vaso-occlusive) pain NOS
|
|
|
D57.8 |
Other sickle-cell disorders [+] Hb-SD disease Hb-SE disease
|
|
D57.80 |
Other sickle-cell disorders without crisis
|
D57.81 |
Other sickle-cell disorders with crisis [+]
|
|
D57.811 |
Other sickle-cell disorders with acute chest syndrome
|
D57.812 |
Other sickle-cell disorders with splenic sequestration
|
D57.813 |
Other sickle-cell disorders with cerebral vascular involvement
Code also |
, if applicable: cerebral infarction (I63.-)
|
|
D57.814 |
Other sickle-cell disorders with dactylitis
|
D57.818 |
Other sickle-cell disorders with crisis with other specified complication
Use additional |
code to identify complications, such as: |
Use additional |
cholelithiasis (K80.-) |
Use additional |
priapism (N48.32) |
|
D57.819 |
Other sickle-cell disorders with crisis, unspecified Other sickle-cell disorders with crisis NOS Other sickle-cell disorders with (vaso-occlusive) pain NOS
|
|
|
|
D58 |
Other hereditary hemolytic anemias [+]
Excludes 1: |
hemolytic anemia of the newborn (P55.-)
|
|
|
D58.0 |
Hereditary spherocytosis Acholuric (familial) jaundice Congenital (spherocytic) hemolytic icterus Minkowski-Chauffard syndrome
|
D58.1 |
Hereditary elliptocytosis Elliptocytosis (congenital) Ovalocytosis (congenital) (hereditary)
|
D58.2 |
Other hemoglobinopathies Abnormal hemoglobin NOS Congenital Heinz body anemia Hb-C disease Hb-D disease Hb-E disease Hemoglobinopathy NOS Unstable hemoglobin hemolytic disease
Excludes 1: |
familial polycythemia (D75.0) Hb-M disease (D74.0) hemoglobin E-beta thalassemia (D56.5) hereditary persistence of fetal hemoglobin [HPFH] (D56.4) high-altitude polycythemia (D75.1) methemoglobinemia (D74.-) other hemoglobinopathies with thalassemia (D56.8)
|
|
D58.8 |
Other specified hereditary hemolytic anemias Stomatocytosis
|
D58.9 |
Hereditary hemolytic anemia, unspecified
|
|
D59 |
Acquired hemolytic anemia [+]
|
|
D59.0 |
Drug-induced autoimmune hemolytic anemia
Use additional |
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5) |
|
D59.1 |
Other autoimmune hemolytic anemias [+]
Excludes 2: |
Evans syndrome (D69.41) hemolytic disease of newborn (P55.-) paroxysmal cold hemoglobinuria (D59.6)
|
|
|
D59.10 |
Autoimmune hemolytic anemia, unspecified
|
D59.11 |
Warm autoimmune hemolytic anemia Warm type (primary) (secondary) (symptomatic) autoimmune hemolytic anemia Warm type autoimmune hemolytic disease
|
D59.12 |
Cold autoimmune hemolytic anemia Chronic cold hemagglutinin disease Cold agglutinin disease Cold agglutinin hemoglobinuria Cold type (primary) (secondary) (symptomatic) autoimmune hemolytic anemia Cold type autoimmune hemolytic disease
|
D59.13 |
Mixed type autoimmune hemolytic anemia Mixed type autoimmune hemolytic disease Mixed type, cold and warm, (primary) (secondary) (symptomatic) autoimmune hemolytic anemia
|
D59.19 |
Other autoimmune hemolytic anemia
|
|
D59.2 |
Drug-induced nonautoimmune hemolytic anemia Drug-induced enzyme deficiency anemia
Use additional |
code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5) |
|
D59.3 |
Hemolytic-uremic syndrome [+]
Code also |
, if applicable, any associated: acute kidney failure (N17.-) chronic kidney disease (N18.-)
|
|
|
D59.30 |
Hemolytic-uremic syndrome, unspecified Hemolytic-uremic syndrome NOS
|
D59.31 |
Infection-associated hemolytic-uremic syndrome Shiga toxin-producing E. coli [STEC] related hemolytic uremic syndrome Typical hemolytic uremic syndrome
Use additional |
code to identify associated infection, such as : |
Use additional |
E. coli infection (B96.2-) |
Use additional |
Human immunodeficiency virus [HIV] disease (B20) |
Use additional |
Pneumococcal meningitis (G00.1) |
Use additional |
Pneumococcal pneumonia (J13) |
Use additional |
Sepsis due to Streptococcus pneumoniae (A40.3) |
Use additional |
Shigella dysenteriae (A03.9) |
Use additional |
Streptococcus pneumoniae as the cause of diseases classified elsewhere (B95.3) |
|
D59.32 |
Hereditary hemolytic-uremic syndrome Atypical hemolytic uremic syndrome with an identified genetic cause
Code also |
, if applicable: defects in the complement system (D84.1) methylmalonic acidemia (E71.120)
|
|
D59.39 |
Other hemolytic-uremic syndrome Atypical (nongenetic) hemolytic uremic syndrome Secondary hemolytic-uremic syndrome
Code first |
, if applicable, any associated: COVID-19 (U07.1) complications of kidney transplant (T86.1-) complications of heart transplant (T86.2-) complications of liver transplant (T86.4-)
|
Code also |
, if applicable, any associated condition, such as: hypertensive emergency (I16.1) malignant neoplasm (C00-C96) systemic lupus erythematosus (M32.-)
|
Use additional |
code, if applicable, for adverse effect to identify drug (T36-T50 with fifth or sixth character 5) |
|
|
D59.4 |
Other nonautoimmune hemolytic anemias Mechanical hemolytic anemia Microangiopathic hemolytic anemia Toxic hemolytic anemia
|
D59.5 |
Paroxysmal nocturnal hemoglobinuria [Marchiafava-Micheli]
Excludes 1: |
hemoglobinuria NOS (R82.3)
|
|
D59.6 |
Hemoglobinuria due to hemolysis from other external causes Hemoglobinuria from exertion March hemoglobinuria Paroxysmal cold hemoglobinuria
Use additional |
code (Chapter 20) to identify external cause |
Excludes 1: |
hemoglobinuria NOS (R82.3)
|
|
D59.8 |
Other acquired hemolytic anemias
|
D59.9 |
Acquired hemolytic anemia, unspecified Idiopathic hemolytic anemia, chronic
|
|