List of Major Diagnostic Categories

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The Major Diagnostic Categories (MDC) are formed by dividing all possible principal diagnoses into 25 mutually exclusive diagnosis areas. MDC codes, like diagnosis-related group (DRG) codes, are primarily a claims and administrative data element unique to the United States medical care reimbursement system. DRG codes also are mapped, or grouped, into MDC codes.
The diagnoses in each MDC correspond to a single organ system or cause and, in general, are associated with a particular medical specialty. MDC 1 to MDC 23 are grouped according to principal diagnoses. Patients are assigned to MDC 24 (Multiple Significant Trauma) with at least two significant trauma diagnosis codes (either as principal or secondaries) from different body site categories. Patients assigned to MDC 25 (HIV Infections) must have a principal diagnosis of an HIV Infection or a principal diagnosis of a significant HIV related condition and a secondary diagnosis of an HIV Infection.
MDC 0, unlike the others, can be reached from a number of diagnosis/procedure situations, all related to transplants. This is due to the expense involved for the transplants so designated and because these transplants can be needed for a number of reasons which do not all come from one diagnosis domain. DRGs which reach MDC 0 are assigned to the MDC for the principal diagnosis instead of to the MDC associated with the designated DRG.

Major Diagnostic Category Description
01 Diseases & Disorders of the Nervous System
02 Diseases & Disorders of the Eye
03 Diseases & Disorders of the Ear, Nose, Mouth & Throat
04 Diseases & Disorders of the Respiratory System
05 Diseases & Disorders of the Circulatory System
06 Diseases & Disorders of the Digestive System
07 Diseases & Disorders of the Hepatobiliary System & Pancreas
08 Diseases & Disorders of the Musculoskeletal System & Connective Tissue
09 Diseases & Disorders of the Skin, Subcutaneous Tissue & Breast
10 Endocrine, Nutritional & Metabolic Diseases & Disorders
11 Diseases & Disorders of the Kidney & Urinary Tract
12 Diseases & Disorders of the Male Reproductive System
13 Diseases & Disorders of the Female Reproductive System
14 Pregnancy, Childbirth & the Puerperium
15 Newborns & Other Neonates with Conditions Originating in Perinatal Period
16 Diseases & Disorders of Blood, Blood Forming Organs, Immunologic Disorders
17 Myeloproliferative Diseases & Disorders, Poorly Differentiated Neoplasms
18 Infectious & Parasitic Diseases, Systemic or Unspecified Sites
19 Mental Diseases & Disorders
20 Alcohol/Drug Use & Alcohol/Drug Induced Organic Mental Disorders
21 Injuries, Poisonings & Toxic Effects of Drugs
22 Burns
23 Factors Influencing Health Status & Other Contacts with Health Services
24 Multiple Significant Trauma
25 Human Immunodeficiency Virus Infections

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