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RxHCC Category

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CMS-HCC Category
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The table below contains a crosswalk of the ICD-10-CM codes that are included in the RxHCC Model v05 (2017, 2018, 2019, 2020, 2021, 2022) and v08 (2023 and 2024). It includes the RxHCC category descriptions, along with the associated prescription drug hierarchy.


HCC Category Description Disease Hierarchy ICD-10-CM Codes
1 HIV/AIDS ...
5 Opportunistic Infections ...
15 Chronic Myeloid Leukemia 17, 18, 19, 20, 21, 22 ...
16 Multiple Myeloma and Other Hematologic Cancers 17, 18, 19, 20, 21, 22 ...
17 Secondary Cancer of Bone and Kidney 18, 19, 20, 21, 22 ...
18 Secondary Cancer of Lung, Liver, Brain, and Other Sites 19, 20, 21, 22 ...
19 Leukemias and Other Hematologic Cancers 20, 21, 22 ...
20 Lung, Kidney, and Other Cancers; Secondary Cancer of Lymph Nodes and Other Sites 21, 22 ...
21 Lymphomas and Other Hematologic Cancers 22 ...
22 Prostate, Breast, Bladder, and Other Cancers and Tumors ...
30 Diabetes with Complications 31 ...
31 Diabetes without Complication ...
40 Alpha - 1 - Antitrypsin Deficiency 43 ...
41 Lysosomal Storage Disorders 43 ...
42 Acromegaly and Other Endocrine and Metabolic Disorders 43 ...
43 Pituitary, Adrenal Gland, and Other Endocrine and Metabolic Disorders ...
44 Thyroid Disorders ...
47 Disorders of Lipoid Metabolism ...
54 Chronic Viral Hepatitis C 55 ...
55 Acute or Unspecified Viral Hepatitis C ...
56 Chronic Viral Hepatitis B and Other Specified Chronic Viral Hepatitis ...
59 Primary Biliary Cirrhosis ...
65 Chronic Pancreatitis 66 ...
66 Pancreatic Disorders and Intestinal Malabsorption, Except Pancreatitis ...
67 Inflammatory Bowel Disease ...
80 Aseptic Necrosis of Bone ...
81 Psoriatic Arthropathy 83, 84, 316 ...
82 Systemic Sclerosis 83, 84 ...
83 Rheumatoid Arthritis and Other Inflammatory Polyarthropathy 84 ...
84 Systemic Lupus Erythematosus and Other Systemic Connective Tissue Disorders 317 ...
87 Osteoporosis, Vertebral and Pathological Fractures ...
95 Sickle Cell Anemia ...
96 Acquired Hemolytic, Aplastic, and Sideroblastic Anemias ...
98 Hereditary Angioedema and Other Defects in the Complement System ...
99 Immune Disorders ...
100 Immune Thrombocytopenic Purpura ...
111 Alzheimer's Disease 112 ...
112 Dementia, Except Alzheimer's Disease ...
130 Schizophrenia and Other Psychosis 131, 132, 133 ...
131 Bipolar Disorders 132, 133 ...
132 Depression 133 ...
133 Anxiety and Other Psychiatric Disorders ...
146 Profound or Severe Intellectual Disability/ Developmental Disorder 147, 148 ...
147 Moderate Intellectual Disability / Developmental Disorder 148 ...
148 Mild or Unspecified Intellectual Disability / Developmental Disorder ...
153 Myasthenia Gravis and Other Myoneural Disorders ...
154 Amyotrophic Lateral Sclerosis and Other Motor Neuron Disease ...
155 Spinal Cord Disorders ...
157 Chronic Inflammatory Demyelinating Polyneuritis 158 ...
158 Inflammatory and Toxic Neuropathy ...
159 Multiple Sclerosis ...
160 Huntington Disease ...
161 Parkinson Disease ...
163 Intractable Epilepsy 164 ...
164 Epilepsy and Other Seizure Disorders, Except Intractable Epilepsy ...
166 Migraine Headaches ...
168 Trigeminal and Postherpetic Neuralgia ...
183 Pulmonary Arterial Hypertension 184, 186, 187 ...
184 Pulmonary Hypertension, Except Arterial, and Other Pulmonary Heart Disease 186, 187 ...
186 Heart Failure 187 ...
187 Hypertension ...
188 Coronary Artery Disease ...
191 Ventricular Septal Defect and Major Congenital Heart Disorders ...
193 Atrial Arrhythmias ...
207 Spastic Hemiplegia ...
215 Venous Thromboembolism ...
225 Cystic Fibrosis 229 ...
226 Idiopathic Pulmonary Fibrosis and Systemic Sclerosis with Lung Involvement 227, 229 ...
227 Pulmonary Fibrosis, Except Idiopathic 229 ...
228 Severe Persistent Asthma 229 ...
229 Chronic Obstructive Pulmonary Disease, Bronchiectasis, and Other Asthma ...
243 Glaucoma, Open - Angle or Moderate/ Severe Stage 244 ...
244 Other Non - Acute Glaucoma ...
260 Kidney Transplant Status 261, 262, 263, 396 ...
261 Dialysis Status, Including End Stage Renal Disease 262, 263 ...
262 Chronic Kidney Disease Stage 5 263 ...
263 Chronic Kidney Disease Stage 4 ...
311 Chronic Ulcer of Skin, Except Pressure ...
314 Pemphigus, Pemphigoid, and Other Bullous Skin Disorders ...
316 Psoriasis, Except with Arthropathy ...
317 Discoid Lupus Erythematosus ...
355 Narcolepsy and Cataplexy ...
395 Stem Cell, Including Bone Marrow, Transplant Status/ Complications ...
396 Heart, Lung, Liver, Intestine, or Pancreas Transplant Status ...

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